Identification of specific markers for human pluripotent stem cell-derived small extracellular vesicles. Yang Wang, et al. Extracell Vesicles, 2024

PM2.5-derived exosomal long noncoding RNA PAET participates in childhood asthma by enhancing DNA damage via m6 A-dependent OXPHOS regulation. Rui Zheng, Fang Gao, Yanping Xiao, Jiayuan Liang, Zhenguang Mao, Cong Gan,Hui Song, Mulong Du, Meilin Wang, Man Tian, Zhengdong Zhang. Environment International, 2024

M2 macrophages secrete glutamate-containing extracellular vesicles to alleviate osteoporosis by reshaping osteoclast precursor fate. Xiaoyuan Huang, Yanhua Lan, Jiahui Shen, Xiaomin Zhao, Yanyan Zhou, Wenzhi Wu, Jiajie Mao, Yuzhu Wu, Zhijian Xie, and Zhuo Chen. Volume 32, 2024

DNA four-way junction-driven dual-rolling circle amplification sandwich-type aptasensor for ultra-sensitive and specific detection of tumor-derived exosomes. Zhuyang Zhao, Sha Yang, Xiaoqi Tang, Liu Feng, Zishan Ding, Zhiguo Chen, Xing Luo, Ruijia Deng, Jing Sheng, Shuang Xie, Kai Chang, Ming Chen. Biosensors and Bioelectronics, 2024

Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau. Biosensors and Bioelectronics, 2024

Engineered M2 macrophage-derived extracellular vesicles with platelet membrane fusion for targeted therapy of atherosclerosis. Lan Xie, Jinyong Chen, Haochang Hu, et al. Bioactive Materials, 2024

A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate. Massimo Bonora, 3 Claudia Morganti, Keisuke Ito, et al. Cell Stem Cell, 2024

Exosomes derived from impaired liver aggravate alveolar bone loss via shuttle of Fasn in type 2 diabetes mellitus. Jiani Liu, Geng Dou, Bei Li, et al. Bioactive Materials, 2024

Extracellular vesicles released by transforming growth factor-beta 1-preconditional mesenchymal stem cells promote recovery in mice with spinal cord injury. Guoliang Chen, Kuileung Tong,et al. Bioactive Materials, 2024

Rhizoma Drynariae-derived nanovesicles reverse osteoporosis by potentiating osteogenic differentiation of human bone marrow mesenchymal stem cells via targeting ERα signaling. Qing Zhao, Junjie Feng, et al. Acta Pharmaceutica Sinica B, 2024

Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting. Wenjie Ma, Di Wu, Ruipeng Jia, et al. Journal of Controlled Release, 2024

ESBL-Escherichia coli extracellular vesicles mediate bacterial resistance to β-lactam and mediate horizontal transfer of blaCTX-M-55. Heting Xu, Chang Tan, Chao Li, Jinpeng Li, Yun Han, Yizhi Tang, Changwei Lei, Hongning Wang. International Journal of Antimicrobial Agents, 2024

Hypoxia endothelial cells-derived exosomes facilitate diabetic wound healing through improving endothelial cell function and promoting M2 macrophages polarization. Peng Cheng, Xudong Xie, Yingze Zhang, et al. Bioactive Materials, 2024

Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens. Rüdiger Groß, Hanna Reßin, Janis A Müller, et al. Nature microbiology, 2024

Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn’s Disease via SMAD4. Yidong Chen, Junrong Li, Liangru Zhu,et al.Journal of Advanced Research, 2024

CRISPR/Cas12a and aptamer-chemiluminescence based analysis for the relative abundance determination of tumor-related protein positive exosomes for breast cancer diagnosis. Xiaotian Guan, Jingru Zhao, Shuqing Sun, et al. Biosensors and Bioelectronics, 2024

3D printing of interferon γ-preconditioned NSC-derived exosomes/collagen/chitosan biological scaffolds for neurological recovery after TBI. Chong Chen, Zhe-Han, Xiao-Hong Li, et al. Bioactive Materials, 2024

Assessing extracellular vesicles in human biofluids using flow-based analyzers. Krzyzaniak O, Yim K, Peacock B, et al. Adv Healthc Mater, 2023

Modification of adipose mesenchymal stem cells-derived small extracellular vesicles with fibrin-targeting peptide CREKA for enhanced bone repair. Wu Q, Fu X, Li X, et al. Bioactive Materials, 2023

A compendium of single extracellular vesicle flow cytometry. Joshua A Welsh et al. J Extracell Vesicles, 2023

TOP-EV: Technology of protein loading through Extracellular Vesicle is a versatile platform for intracellular protein delivery. Nazma F Ilahibaks et al. J Control Release, 2023

Bile exosomal miR-182/183-5p increases cholangiocarcinoma stemness and progression by targeting HPGD and increasing PGE2 generation. Lizhuang Shu 1, Xingyong Li,et al. Hepatology, 2023

Quantitative assessment of lipophilic membrane dye-based labelling of extracellular vesicles by nano-flow cytometry. Chen Chen, Niangui Cai, Xiaomei Yan et al. Journal of Advanced Research, 2023

Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications. Zhengrong Zhang, Tsuneya Ikezu et al. J Extracell Vesicles, 2023

Encapsulation of Nano-Bortezomib in Apoptotic Stem Cell-Derived Vesicles for the Treatment of Multiple Myeloma. Zeyuan Cao, Peiyi Li, Songtao Shi, Xiaoxing Kou, et al. Small, 2023

Ultrafast and Controlled Capturing, Loading, and Release of Extracellular Vesicles by a Portable Microstructured Electrochemical Fluidic Device. Vadim Krivitsky, Adva Krivitsky, Valeria Mantella et al. Adv. Mater, 2023

Simultaneous subset tracing and miRNA profiling of tumor-derived exosomes via dual-surface-protein orthogonal barcoding. Yanmei Lei1, Xiaochen Fei1, Yue Ding. Sci Adv, 2023

Engineered Extracellular Vesicles in Wound Healing: Design, Paradigms, and Clinical Application. Yuheng Liao, Zhenhe Zhang, Lizhi Ouyang, Bobin Mi, Guohui Liu. Small, 2023

An Aptamer-Based Nanoflow Cytometry Method for the Molecular Detection and Classification of Ovarian Cancers through Profiling of Tumor Markers on Small Extracellular Vesicles. Jin Li, Yingying Li, Qin Li, Lu Sun, et al. Angewandte Chemie, 2023

Graphene Sensor Arrays for Rapid and Accurate Detection of Pancreatic Cancer Exosomes in Patients’ Blood Plasma Samples. Tianyi Yin,Lizhou Xu,Bruno Gil,et al. ACS nano, 2023

Deciphering the Heterogeneity Landscape of Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles for Precise Selection in Translational Medicine. Ye Li, Yin-Hsueh Chen, et al. Advanced Healthcare Materials, 2023

Programmed Death Ligand-1-Overexpressing Donor Exosomes Mediate Donor-Specific Immunosuppression by Delivering Co-Inhibitory Signals to Donor-Specific T Cells. Xuewei Luo, Guicheng Du, Yufei Long, Mengchao Zheng, Bingye Chen, Weiting Li, Guoliang Yan, Zhongquan Qi, Tianshu Lan. Advanced Healthcare Materials, 2023

Hierarchically Injectable Hydrogel Sequentially Delivers AntagomiR-467a-3p-Loaded and AntagomiR-874-5p-Loaded Satellite-Cell-Targeting Bioengineered Extracellular Vesicles Attenuating Sarcopenia. Hanhao Dai, Jun Luo, Lili Deng, Chao Song, Zhibo Deng, Yijing Wu, Song Gu,and Jie Xu. Adv Healthc Mater, 2023

Detection of the interactions of tumour derived extracellular vesicles with immune cells is dependent on EV-labelling methods. Luisa Loconte,et al. J Extracell Vesicles, 2023

An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood.Blanca V. Rodriguez, Yi Wen, et al. J Extracell Vesicles, 2023

TOP-EVs: Technology of Protein delivery through Extracellular Vesicles is a versatile platform for intracellular protein delivery. Nazma F, Ilahibaks, Arif I, Ardisasmita, et al. Journal of Controlled Release, 2023

Skeletal muscle-derived extracellular vesicles transport glycolytic enzymes to mediate muscle-to-bone crosstalk. Shixing Ma, Xiaotao Xing, Haisen Huang, Xin Gao, Xun Xu, Jian Yang, Chengcheng Liao, Xuanhao Zhang, Jinglun Liu, Weidong Tian, Li Liao. Cell Metabolism, 2023

Exosomal miRNA analysis provides new insights into exposure to nanoplastics and okadaic acid. Linhong Yan, Peichun Lin, Zijie Wu, et al. Science of The Total Environment, 2023

Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p. Sheng Li, Ke Yang, Guanwei Fan, et al. Journal of Controlled Release, 2023

Surface display of functional moieties on extracellular vesicles using lipid anchors. Wenyi Zheng, Melanie Schürz, Samir E.L. Andaloussi, et al. Journal of Controlled Release, 2023

Exosome delivery to the testes for dmrt1 suppression: A powerful tool for sex-determining gene studies. Tengfei Zhu, Ming Kong, Yingying Yu, et al. Journal of Controlled Release, 2023

Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis. Jie Lian, Xinxing Zhu, Juntang Lin, et al. Molecular Therapy, 2023

Red blood cell extracellular vesicles deliver therapeutic siRNAs to skeletal muscles for treatment of cancer cachexia. Boya Peng, Yuqi Yang, et al. Molecular Therapy, 2023

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction. Zheng R, Zhang K, Tan S, et al. Molecular Cancer, 2022

Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice. He F, Li W N, Li X X, et al. Theranostics, 2022

A CAR T-inspiring platform based on antibody-engineered exosomes from antigen-feeding dendritic cells for precise solid tumor therapy. Fan M, Liu H, Yan H, et al. Biomaterials, 2022

Fine Particulate Matter Induces Childhood Asthma Attacks via Extracellular Vesicle‐Packaged Let‐7i‐5p‐Mediated Modulation of the MAPK Signaling Pathway. Zheng R, Du M, Tian M, et al. Advanced Science, 2022

Curcumin primed ADMSCs derived small extracellular vesicle exert enhanced protective effects on osteoarthritis by inhibiting oxidative stress and chondrocyte apoptosis. Xu C, Zhai Z, Ying H, et al. Journal of Nanobiotechnology, 2022

Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry. Liu H, Tian Y, Xue C, et al. Journal of Extracellular Vesicles, 2022

Quantification of Available Ligand Density on the Surface of Targeted Liposomal Nanomedicines at the Single-Particle Level. Chen C, Zhou Y, Chen C, et al. ACS nano, 2022

Hybridization chain reaction-mediated Fe2MoO4 bimetallic nanozyme for colorimetric risk prediction of bladder cancer. Fu Y, Zhao Z, Shi Y, et al. Biosensors and Bioelectronics, 2022

Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma–Contributions of platelet extracellular vesicles in plasma samples. Karimi N, Dalirfardouei R, Dias T, et al. Journal of Extracellular Vesicles, 2022

Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry. Liu H, Tian Y, Xue C, et al. Journal of extracellular vesicles, 2022

Apoptotic extracellular vesicles are metabolized regulators nurturing the skin and hair. Ma L, Chen C, Liu D, et al. Bioactive Materials, 2022

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction. Zheng R, Zhang K, Tan S, et al. Molecular cancer, 2022

Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy. Jayasinghe M K, Pirisinu M, Yang Y, et al. Theranostics, 2022

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles. Céspedes P F, Jainarayanan A, Fernández-Messina L, et al. Nature Communications, 2022

Proteomic analysis of MSC‐derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions. Zhang X, Tang J, Kou X, et al. Journal of Extracellular Vesicles, 2022

Exosomal LBH inhibits epithelial-mesenchymal transition and angiogenesis in nasopharyngeal carcinoma via downregulating VEGFA signaling. Wu A, Luo N, Xu Y, et al. International journal of biological sciences, 2022

Exosomes derived from immunogenically dying tumor cells as a versatile tool for vaccination against pancreatic cancer. Zhou W, Chen X, Zhou Y, et al. Biomaterials, 2022

Apoptotic Vesicles Inherit SOX2 from Pluripotent Stem Cells to Accelerate Wound Healing by Energizing Mesenchymal Stem Cells. Qu Y, He Y, Meng B, et al. Acta Biomaterialia, 2022

MiRNA 24-3p-rich exosomes functionalized DEGMA-modified hyaluronic acid hydrogels for corneal epithelial healing. Sun X, Song W, Teng L, et al. Bioactive Materials, 2022

Injectable Bacteria-Sensitive Hydrogel Promotes Repair of Infected Fractures via Sustained Release of miRNA Antagonist. Yu C, Chen L, Zhou W, et al. ACS Applied Materials & Interfaces, 2022

Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma–Contributions of platelet extracellular vesicles in plasma samples. Karimi N, Dalirfardouei R, Dias T, et al. Journal of extracellular vesicles, 2022

Serum extracellular vesicles profiling is associated with COVID‐19 progression and immune responses. Yim K H W, Borgoni S, Chahwan R. Journal of extracellular biology, 2022

Widespread of Potential Pathogen-Derived Extracellular Vesicles Carrying Antibiotic Resistance Genes in Indoor Dust. Qin Y, Guo Z, Huang H, et al. Environmental Science & Technology, 2022

Proteomic analysis of MSC‐derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions. Zhang X, Tang J, Kou X, et al. Journal of Extracellular Vesicles, 2022

Hybrid Biomimetic Nanovesicles to Drive High Lung Biodistribution and Prevent Cytokine Storm for ARDS Treatment. Qiao Q, Liu X, Cui K, et al. ACS nano, 2022

Fine Particulate Matter Induces Childhood Asthma Attacks via Extracellular Vesicle‐Packaged Let‐7i‐5p‐Mediated Modulation of the MAPK Signaling Pathway. Zheng R, Du M, Tian M, et al. Advanced Science, 2022

KIM-1 augments hypoxia induced tubulointerstitial inflammation through uptake of small extracellular vesicles by tubular epithelial cells. Chen J, Tang T T, Cao J Y, et al. Molecular Therapy, 2022

Bladder Cancer‐Derived Small Extracellular Vesicles Promote Tumor Angiogenesis by Inducing HBP‐Related Metabolic Reprogramming and SerRS O‐GlcNAcylation in Endothelial Cells. Li X, Peng X, Zhang C, et al. Advanced Science, 2022

Adipocyte‐Derived Exosomal MTTP Suppresses Ferroptosis and Promotes Chemoresistance in Colorectal Cancer. Zhang Q, Deng T, Zhang H, et al. Advanced Science, 2022

Enhanced therapeutic effects of Mesenchymal Stem Cell-derived Extracellular Vesicles within Chitosan Hydrogel in the treatment of Diabetic Foot Ulcers. Yang S, Chen S, Lin C, et al. J Mater Sci Mater Med, 2022

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction. Zheng R, Zhang K, Tan S, et al. Molecular cancer, 2022

MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis. Gan J, Liu S, Zhang Y, et al. Experimental & Molecular Medicine, 2022

Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small extracellular vesicles. Visan K S, Lobb R J, Ham S, et al. Journal of Extracellular Vesicles, 2022

Eliminating the original cargos of glioblastoma cell-derived small extracellular vesicles for efficient drug delivery to glioblastoma with improved biosafety. Guo Y, Hu G, Xia Y, et al. Bioactive materials, 2022

Emodin attenuates severe acute pancreatitis-associated acute lung injury by suppressing pancreatic exosome-mediated alveolar macrophage activation. Hu Q, Yao J, Wu X, et al. Acta Pharmaceutica Sinica B, 2022

MiRNA 24-3p-rich exosomes functionalized DEGMA-modified hyaluronic acid hydrogels for corneal epithelial healing. Sun X, Song W, Teng L, et al. Bioactive Materials, 2022

Exosomes—Nature’s Lipid Nanoparticles, a Rising Star in Drug Delivery and Diagnostics. Rumiana Tenchov, Janet M. Sasso, Xinmei Wang, et al. ACS Nano, 2022

Eliminating the original cargos of glioblastoma cell-derived small extracellular vesicles for efficient drug delivery to glioblastoma with improved biosafety. Yuhang Guo, Guowen Hu, Zhifeng Deng, et al. Bioactive Materials, 2022

A Versatile Platform for Generating Engineered Extracellular Vesicles with Defined Therapeutic Properties. Dooley K, McConnell, R. E. et al. Molecular Therapy, 2021

Characterization of extracellular vesicles and artificial nanoparticles with four orthogonal single-particle analysis platforms. Mallick E R., Arab, Huang Y. et al. bioRxiv, 2021

Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge? Vogel R, Savage J, Muzard J, et al. Journal of Extracellular Vesicles, 2021

Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium. Dong L, Zieren R C, et al. Journal of Extracellular Vesicles, 2021

Establishment of a simplified dichotomic size-exclusion chromatography for isolating extracellular vesicles toward clinical applications. Jiahui, Guo, et al. Journal of extracellular vesicles, 2021

NIR-II emissive lateral flow immunoassay for accurate determination of tumor marker in hemolysis. Chen, Rui, et al. Sensors and Actuators B: Chemical, 2021

Extracellular Vesicle-Based Coatings Enhance Bioactivity of Titanium Implants—SurfEV Pansani, T N, Phan T H, Chrzanowski W, et al. Nanomaterials, 2021

New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles Phan T H, Divakarla S K, Chrzanowski W, et al. Frontiers in Bioengineering and Biotechnology, 2021

Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of  T cell immunological synapses L Dustin M, Cespedes P, et al. bioRxiv, 2021

BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells. Zhang, Xin, et al. Oncogene, 2021

A magnetic bead-mediated selective adsorption strategy for extracellular vesicle separation and purification. Fang X, Chen C, Liu B, et al. Acta Biomaterialia, 2021

Extracellular vesicles isolated by size-exclusion chromatography present suitability for RNomics analysis in plasma.Yang, Y, Wang, Y, Wei S, et al. Journal of Translational Medicine, 2021

Considerations for MESF-bead based assignment of absolute fluorescence values to nanoparticles and extracellular vesicles by flow cytometry. Lozano-Andrés, Estefanía, et al. bioRxiv, 2021

Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration. Zhang Z, Xu R, Yang Y, et al. biotechnology, 2021

Small extracellular vesicles from human adipose-derived mesenchymal stromal cells: a potential promoter of fat graft survival. Chen A, Tang S, He J, et al. Stem Cell Research & Therapy, 2021

The Role of Small Extracellular Vesicles Derived from Lipopolysaccharide-preconditioned Human Dental Pulp Stem Cells in Dental Pulp Regeneration. Chen, Wen-Jin, et al. Journal of Endodontics, 2021

Controlled release of MSC-derived small extracellular vesicles by an injectable Diels-Alder crosslinked hyaluronic acid/PEG hydrogel for osteoarthritis improvement. Yang Y, Zhu Z, Gao R, et al. Acta Biomaterialia, 2021

MicroRNA -370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis. Li C, Deng C, Zhou T, et al. International journal of biological sciences, 2021

Neural stem cell-derived exosomes regulate neural stem cell differentiation through miR-9-Hes1 axis. Yuan P, Ding L, Chen H, et al. Frontiers in Cell and Developmental Biology, 2021

Plasma-derived exosomal ALIX as a novel biomarker for diagnosis and classification of pancreatic cancer. Yang J, Zhang Y, Gao X, et al. Frontiers in Oncology, 2021

Priming with Toll-Like Receptor 3 Agonist Poly (I: C) Enhances Content of Innate Immune Defense Proteins but not MicroRNAs in Human Mesenchymal Stem Cell-Derived Extracellular Vesicles. Pierce, Lisa, and Wendy E. Kurata. Frontiers in Cell and Developmental Biology, 2021

Comparison and Investigation of Exosomes Derived from Platelet-Rich Plasma Activated by Different Agonists. Rui S, Yuan Y, Du C, et alCell Transplantation, 2021

Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses. Pablo F., As J, Lola Fe -Me, et al. BioRxiv, 2021

Platelet Rich Plasma-Derived Exosomal USP15 Promotes Cutaneous Wound Healing via Deubiquitinating EIF4A1. Xu, Y, Lin Z, He L, et al. Oxid Med Cell Longev, 2021

Extracellular vesicles isolated by size-exclusion chromatography present suitability for RNomics analysis in plasma. Yang Y, Wang Y, Wei S, et al. Journal of Translational Medicine, 2021

Considerations for MESF-bead based assignment of absolute fluorescence values to nanoparticles and extracellular vesicles by flow cytometry. Lozano-Andrés, E.Van Den Broeck, et al. bioRxiv, 2021

Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release. Zhou, Lin, et al. Skeletal muscle, 2021

Exosomes Derived from Nerve Stem Cells Loaded with FTY720 Promote the Recovery after Spinal Cord Injury in Rats by PTEN/AKT Signal Pathway. Chen J, Zhang C, Li S, et al. Journal of Immunology Research, 2021

Comparison of The Variability of Small Extracellular Vesicles Derived From Human Liver Cancer Tissues And Cultured From The Tissue Explants Based On A Simple Enrichment Method: Yield, Purity And Molecular Markers. Chen J, Jiao Z, Mo J, et al. Stem Cell Rev Rep, 2021

The Role of Small Extracellular Vesicles Derived from Lipopolysaccharide-preconditioned Human Dental Pulp Stem Cells in Dental Pulp Regeneration. Chen W J, Xie J, Lin X, et al. Journal of Endodontics, 2021

Compositional Features of Distinct Microbiota Base on Serum Extracellular Vesicle Metagenomics Analysis in Moderate to Severe Psoriasis Patients. Chang C J, Zhang J, Tsai Y L, et al. Cells, 2021

PD-L1 detection on circulating tumor-derived extracellular vesicles (T-EVs) from patients with lung cancer. Wu F, Gu Y, Kang B, et al. Translational Lung Cancer Research, 2021

Isolation and characterization of extracellular vesicle subpopulations from tissues. Crescitelli, Rossella, Cecilia Lässer, and Jan Lötvall. Nature Protocols, 2021

Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs. Chen H, Xie Y, Li Y, et al. Journal of Assisted Reproduction and Genetics, 2021

Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution. Silva, A. M, Lázaro‐Ibáñez, et al. Journal of Extracellular Vesicles, 2021

High-Throughput Simultaneous mRNA Profiling Using nCounter Technology Demonstrates That Extracellular Vesicles Contain Different mRNA Transcripts Than Their Parental Prostate Cancer Cells. Dong, L. Huang, C. Y. Johnson, et al. Analytical Chemistry, 2021

Scaled preparation of extracellular vesicles from conditioned media. Staubach, Simon, et al. Advanced Drug Delivery Reviews, 2021

Abnormal expression profile of plasma-derived exosomal microRNAs in patients with treatment-resistant depression. Li L D, Naveed M, Du Z W, et al. Human genomics, 2021

General and mild modification of food-derived extracellular vesicles for enhanced cell targeting. Chen C, Sun M, Liu X, et al. Nanoscale, 2021

Opportunities and Pitfalls of Fluorescent Labeling Methodologies for Extracellular Vesicle Profiling on High-Resolution Single-Particle Platforms. Fortunato D, Mladenović D, Criscuoli M, et al. International Journal of Molecular Sciences, 2021

Comparison of the Variability of Small Extracellular Vesicles Derived from Human Liver Cancer Tissues and Cultured from the Tissue Explants Based on a Simple Enrichment Method. Chen J, Jiao Z, Mo J, et al. Stem Cell Reviews and Reports, 2021

A Hypercoagulable Hematological Metastasis Breast Cancer Model. Yang W J, Zhang G L, Cao K X, et al. BioMed Research International, 2021

Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs. Chen H, Xie Y, Li Y, et al. Journal of Assisted Reproduction and Genetics, 2021

Distinct Proteomic Profiling of Plasma Extracellular Vesicles from Moderate-to-Severe Atopic Dermatitis Patients. Chang C J, Wang H Q, Zhang J, et al. Clinical, Cosmetic and Investigational Dermatology, 2021

Cardiac microvascular functions improved by MSC-derived exosomes attenuate cardiac fibrosis after ischemia–reperfusion via PDGFR-β modulation. Wang X, Bai L, Liu X, et al. International Journal of Cardiology, 2021

Serum exosome-derived biomarkers for the early detection of oral squamous cell carcinoma. Guo H, Jiang W, Huang S, et al. Molecular and Cellular Biochemistry, 2021

Periodontal ligament fibroblast-Derived Exosomes Induced by Compressive Force promote macrophage M1 polarization via Yes-Associated Protein. Zhao M, Ma Q, Zhao Z, et al. Archives of Oral Biology, 2021

Articular chondrocyte-derived extracellular vesicles promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy. Ma K, Zhu B, Wang Z, et al. Journal of Nanobiotechnology, 2020

Exosomal miR-100-5p inhibits osteogenesis of BMSCs and angiogenesis of VECs by suppressing BMPR2/Smad1/5/9 signaling pathway. Yang, Wu, et al. Stem Cell Res Ther, 2020

MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis. Zheng J, Kong Y, Hu X, et al. Stem cell research & therapy, 2020

Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Improve Ovarian Function and Proliferation of Premature Ovarian Insufficiency by Regulating the Hippo Signaling Pathway. Li Z, Zhang M, Zheng J, et al. Frontiers in Endocrinology, 2021

Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles. Huang, Yiyao, et al. Journal of Biomaterials and Tissue Engineering, 2020

miR-101 Inhibits AKT/mTOR and Attenuates Oral Cancer Cell Colony Formation and Epithelial-Mesenchymal Transition. Long, Fei, et al. Journal of Biomaterials and Tissue Engineering, 2020

p53 Inhibits Lung Cancer Proliferation and Invasion by Regulating miR-34a and Epithelial-Mesenchymal Transition Transformation. Fu, Changyou, et al. Journal of Biomaterials and Tissue Engineering, 2020

Relationships of Alzheimer's disease and apolipoprotein E genotypes with small RNA and protein cargo of brain tissue extracellular vesicles. Huang Y, Driedonks T A, Cheng L, et al. medRxiv, 2020

Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro. Liu Q, Tan Y, Qu T, et al. Life Sciences, 2020

Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer. Wei P, Wu F, Kang B, et al. Journal of extracellular vesicles, 2020

Heparanase from triplenegative breast cancer and platelets acts as an enhancer of metastasis. Yang, W. J, Zhang, et al. International Journal of Oncology, 2020

The future of Extracellular Vesicles as Theranostics–an ISEV meeting report. Soekmadji C, Li B, Huang Y, et al. Journal of Extracellular Vesicles, 2020

Radiation-induced small extracellular vesicles as “carriages” promote tumor antigen release and trigger antitumor immunity. Lin W, Xu Y, Chen X, et al. Theranostics, 2020

Clinical Significance of Circulating Exosomal PD-L1 and Soluble PD-L1 in Nasal-type NK/T-cell Lymphoma Patients，Receiving VIPD Containing Chemotherapy. Jiwei Li, Ping Wei, Ye Guo, et al. Research Square, 2020

Technologies and Standardization in Research on Extracellular Vesicles. Gandham S, Su X, Wood J, et al. Trends in Biotechnology, 2020

Separation of extracellular vesicles by DNA-directed immunocapturing followed by enzymatic release. Brambilla D, Sola L, Chiodi, et al. ChemRixv, 2020

Radiation-induced small extracellular vesicles as “carriages” promote tumor antigen release and trigger antitumor immunity. Lin W, Xu Y, Chen X, et al. Theranostics, 2020

Relationships of Alzheimer’s disease and apolipoprotein E genotypes with small RNA and protein cargo of brain tissue extracellular vesicles. Huang Y, Driedonks T A, Cheng L, et al. medRxiv, 2020

Extracellular vesicles containing host restriction factor IFITM3 inhibited Zika virus infection of fetuses in pregnant mice through trans-placenta delivery.Zou X, Yuan M, Zhang T, et al. Molecular Therapy, 2020

Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer. Wei P, Wu F, Kang B, et al. Journal of Extracellular Vesicles, 2020

The future of Extracellular Vesicles as Theranostics– an ISEV meeting report. Soekmadji C, Li B, Huang Y, et al. Journal of Extracellular Vesicles, 2020

Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles. Jiang W, Ma P, Deng L, et al. Journal of Extracellular Vesicles, 2020

Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry. Tian Y, Gong M, Hu Y, et al. Journal of Extracellular Vesicles, 2020

Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib. Ke C, Hou H, Li J, et al. Cancers, 2020

Small Extracellular Vesicles From Human Adipose-derived Stem Cells: A Potential Promoter of Keeping Fat Graft Survival.  Chen A, Tang S, He J, et al. Stem Cell Research & Therapy, 2020

Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro. Liu Q, Tan Y, Qu T, et al. Life Sciences, 2020

ESC‐sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia. Hu G, Xia Y, Zhang J, et al. Advanced Science, 2020

Increased Interleukin-6 Levels in Neuron-Derived Plasma Small Extracellular Vesicles of Subarachnoid Haemorrhage Patients. Lai N, Yao Y, Yu T, et al. Research Square, 2020

Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke. Xia Y, Ling X, Hu G, et al. Stem Cell Research & Therapy, 2020

The immunomodulatory signature of extracellular vesicles from Cardiosphere-Derived Cells: a proteomic and miRNA profiling. López E, Marinaro F, de Pedro, et al. Frontiers in Cell and Developmental Biology, 2020

Clinical significance of circulating exosomal PD-L1 and soluble PD-L1 in extranodal NK/T-cell lymphoma, nasal-type. Li J. W, Wei P, Guo, et al. American journal of cancer research, 2020

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway. Lv, Y, Chen, J, Hu, J, et al. Frontiers in Pharmacology, 2020

Exosomal CA125 as A Promising Biomarker for Ovarian Cancer Diagnosis. Chen Z, Liang Q, Zeng H, et al. Journal of Cancer, 2020

Thermosensitive Exosome–Liposome Hybrid Nanoparticle‐Mediated Chemoimmunotherapy for Improved Treatment of Metastatic Peritoneal Cancer. Lv Q, Cheng L, Lu Y, et al. Advanced Science, 2020

Exosomal lncRNA RAMP2-AS1 Derived from Chondrosarcoma Cells Promotes Angiogenesis Through miR-2355-5p/VEGFR2 Axis. Cheng C, Zhang Z, Cheng F, et al. OncoTargets and therapy, 2020

Serum Exosomal MicroRNA-21, MicroRNA-126, and PTEN Are Novel Biomarkers for Diagnosis of Acute Coronary Syndrome. Ling H, Guo Z, Shi Y, et al. Frontiers in Physiology, 2020

Clinical Significance of Circulating Exosomal PD-L1 and Soluble PD-L1 in Nasal-type NK/T-cell Lymphoma Patients, Receiving VIPD Containing Chemotherapy. Jiwei Li, Ping Wei, Ye Guo, et al. Research Square, 2020

Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles. Jiang W, Ma P, Deng L, et al. Journal of Extracellular Vesicles, 2020

Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy. Lv P, Liu X, and Liu G et al. Nano Letters, 2019

Plasma Extracellular Vesicle Long RNA Profiling Identifies a Diagnostic Signature for the Detection of Pancreatic Ductal Adenocarcinoma. Yu S, Li Y, and Liao Z, et al. Gut, 2019

Programmable Modulation for Extracellular Vesicles. Wany Y, Melvin R, Bemis L, Worrell G, Wang H. bioRxiv, 2019

Extracellular Vesicles Long RNA Sequencing Reveals Abundant mRNA, circRNA, and lncRNA in Human Blood as Potential Biomarkers for Cancer Diagnosis. Li Y, Zhao J, and Huang S et al. Clinical Chemistry, 2019

Extracellular Vesicles Derived from ODN-stimulated Macrophages Transfer and Activate Cdc42 in Recipient Cells and Thereby Increase Cellular Permissiveness to EV Uptake. Zhang Y, Jin X, and Liang J et al. Science Advances, 2019

Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry. Tian Y, Ma L, Gong M, et al. ACS Nano, 2018

Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells. Zhang Q, Liu R X, Chan K W, et al. Journal of Experimental & Clinical Cancer Research, 2019

Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma. Han Z, Li Y, Zhang J, et al. International Journal of Medical Sciences, 2020

Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells Alleviate Mifepristone-Induced Human Endometrial Stromal Cell Injury. Wang J, Hu R, Xing Q, et al. Stem Cells International, 2020

PTH Derivative promotes wound healing via synergistic multicellular stimulating and exosomal activities. Shen Y F, Huang J H, Wang K.Y, et al. Cell Communication and Signaling, 2020

Articular chondrocyte derived exosomes promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy. Ma K, Zhu B, Wang Z, et al. Journal of Nanobiotechnology, 2020

Seminal plasma exosomes evoke calcium signal via CatSper channel to regulate human sperm function. Zhang X, Song D, Zhou W, et al. bioRxiv, 2020

Exosomes isolated from the plasma of remote ischemic conditioning rats improved cardiac function and angiogenesis after myocardial infarction through targeting Hsp70. Chen Q, Huang M, Wu J, et al. Aging (Albany NY), 2020

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway. Lv Y, Chen J, Hu J, et al. Frontiers in Pharmacology, 2020

Saliva Exosomes-Derived UBE2O Promotes Angiogenesis in Cutaneous Wounds By Targeting SMAD6. Mi B, Chen L, Xiong Y, et al. Journal of Nanobiotechnology, 2020

Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke. Ling X, Zhang G, Xia Y, et al. Journal of Cellular and Molecular Medicine, 2020

Embryonic Stem Cells-Derived Exosomes Endowed with Targeting Properties as Chemotherapeutics Delivery Vehicles for Glioblastoma Therapy. Zhu Q, Ling X, and Deng Z et al. Advanced Science, 2019

Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells. Kim S Y, Joglekar M V, Hardikar A A, et al. J Exp Clin Cancer Res, 2019

Renoprotective Effects of Artemisinin and Hydroxychloroquine Combination Therapy on IgA Nephropathy via Suppressing NF-κB Signaling and NLRP3 Inflammasome Activation by Exosomes in Rats. Bai L, Li J, and Li H et al. Biochemical Pharmacology, 2019

Magnetic-Based Microfluidic Device for On-Chip Isolation and Detection of Tumor-Derived Exosomes. Xu H, Liao C, Zuo P, Liu Z, and Ye B. Analytical Chemistry, 2018

Multiple antibodies identify glypican-1 associated with exosomes from pancreatic cancer cells and serum from patients with pancreatic cancer. Dong C, Huang L, Kalluri R. et al. bioRixv, 2018