Comprehensive LNP Characterization from Cargo to Target Modification Using Nano-Flow Cytometry

Optimizing RNA encapsulation is vital for formulation development and maximizing delivery to target cells to ensure the success of therapeutics and vaccines. However assessing the efficiency of the optimization process remains challenging. One solution is single particle analyses using technologies like nano-flow cytometry. This technology makes it possible to simultaneously size and count lipid nanoparticles (LNPs) whilst identifying the presence of cargo or surface modifications to determine efficacy of the nanoparticle loading or functionalization.

In this GEN webinar, Ben Peacock, PhD, will present the NanoAnalyzer platform and describe how it supports multi-parameter analysis and characterization of biological nanoparticles like LNPs. During the webinar, you’ll learn how technology can be used to identify priority subpopulations within samples using exogenous labeling techniques, and how this allows for quantifying RNA cargo or the surface density of various targeting modalities.


Key highlights include:

  • Identify the presence of cargo and surface modifications

  • Determine the efficacy of nanoparticle loading or functionalization

  • Identify priority subpopulations within samples using exogenous labeling techniques

  • Quantify RNA cargo or the surface density of various targeting modalities 

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert speaker.


🔗 Register Now:

https://lnkd.in/gmmzSRT2

Date: 

Wednesday, July 10, 2024

Time: 

8:00 am PT | 11:00 am ET | 17:00 CET

Register Now

About the speaker

394b6119df9eb5b8889f777b7ce8333.png

Ben Peacock, PhD

Head of Research

NanoFCM

Ben Peacock obtained his Ph.D. from the University of Sheffield, where his research focused on the characterization of biological nanoparticles and their use as non-invasive biomarkers. Currently, Dr. Peacock serves as the Head of Research at NanoFCM, leading the development of applications for nano-flow cytometry (nFCM) characterization of various nanoparticles, such as lipid nanoparticles (LNPs), viruses, virus-like particles and exosomes. With extensive experience in characterization and analytics, Dr. Peacock has successfully led teams in protocol development, process and formulation optimization and provided professional bespoken solutions for clients across EU and NA.