Nano-flow Cytometry is super-sensitive, which allows label free analysis of single silica and gold nanoparticles down to 24 nm and 7 nm, respectively. For viruses, it is able to detect the signals from single MS2 virus (27 nm). Nano-flow cytometry shows a resolution comparable to that of TEM and the throughput of flow cytometric analysis.
The fluorescent signals from single R-phycoerythrin molecules can be acquired individually by nano-flow cytometry, which means the NanoFCM is able to study EV proteins as low as ONE copy.
The fluorescent signals of mRNA which stained with nucleic acid dye presented single and uniform signal during individually by nano-flow cytometry, which means the NanoFCM is able to analysis signle nucleic acid.
Hundreds of nanoparticles can be detected one by one per second, and a highly representative statistical distribution of particle properties can be obtained in 1 minute.